The problem of strong earthquake forecasting is a pressing issue. This issue has attracted special attention from scientists around the world working in this area. Interesting and encouraging results have been obtained over the past 50 years. Geophysical (geomagnetic, geoelectric, ionospheric), geodetic, hydrogeochemical and other methods are particularly widely used. Despite the use of modern equipment, methods of collecting, processing and analyzing the data obtained, there is no clear idea of the spatio-temporal features of the manifestation of precursor anomalies. The results obtained show the most diverse nature of the manifestation of precursors, differing in form, intensity and duration in time. In such a complex situation, anomalous changes in many geological and geophysical parameters have been identified that are not associated with the processes of preparing strong earthquakes or changing the weak seismicity of the region under study. These anomalous changes have a duration of 10–15 days to 10 years or more. They can have different forms and intensities. They are comparable in the noted parameters with anomalies caused by the processes of preparation of strong earthquakes. A distinctive feature of these anomalies is their more frequent manifestation in geological and geophysical parameters. The article examines the features of the manifestation of local anomalous variations of the geomagnetic field of the type under consideration on the territory of Uzbekistan. Determining the nature of the manifestation of these anomalies has scientific and practical significance in solving the problem of forecasting strong earthquakes.